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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $28.05 | Total: $140.25 |
| 1 | 10 | $23.76 | Total: $237.60 |
| 1 | 25 | $20.13 | Total: $503.25 |
| 1 | 50 | $17.16 | Total: $858.00 |
| 1 | 100 | $14.85 | Total: $1,485.00 |
Overview
SYN1143 (AMG-1) is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmolL, respectively.
Chemical Properties
| Molecular Formula | C31H29FN4O5 |
| Molecular Weight | 556.58 |
| CAS Numbers | 913376-84-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC(C)(C)O)n(-c5ccccc5)c4=O)cc3F)ccnc2c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Zhang Y, et, al. Identification of a novel recepteur d'origine nantaisc-met small-molecule kinase inhibitor with antitumor activity in vivo. Cancer Res. 2008 Aug 15;68[16] 6680-7.