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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
CEP-40783 (RXDX-106) is an effective, specific and orally active AXLc-Met inhibitor (IC50: 712 nM). It also inhibits MER and TYRO3 (IC50: 2919 nM).
Chemical Properties
| Molecular Formula | C31H26F2N4O6 |
| Molecular Weight | 588.56 |
| CAS Numbers | 1437321-24-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cc2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c2cc1OC |
Storage and Handling
0C Short Term, -20C Long Term
References
Miknyoczki S, Cheng M, Hudkins R, et al. Abstract C275 CEP-40783 A potent and selective AXLc-Met inhibitor for use in breast, non-small cell lung [NSCLC], and pancreatic cancers.[J]. Molecular Cancer Therapeutics, 2013, 12[11_Supplement] C275-C275.