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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $45.05 | Total: $225.25 |
| 1 | 10 | $38.16 | Total: $381.60 |
| 1 | 25 | $32.33 | Total: $808.25 |
| 1 | 50 | $27.56 | Total: $1,378.00 |
| 1 | 100 | $23.85 | Total: $2,385.00 |
Overview
AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. It demonstrates potent single-digit nM growth inhibition across a broad cell panel.
Chemical Properties
| Molecular Formula | C24H26FN7O3 |
| Molecular Weight | 479.51 |
| CAS Numbers | 2248003-60-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COCCOc1cc(F)c2c(Nc3ccc(NC(=O)Cn4cc(nn4)C(C)C)cc3)ncnc2c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Kettle JG, et al. Discovery of N-[4-{[5-Fluoro-7-[2-methoxyethoxy] quinazolin-4-yl]amino} phenyl]-2-[4-[propan-2-yl]-1 H-1,2,3-triazol-1-yl]acetamide [AZD3229], a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors. J Med Chem. 2018 Oct 11;61[19] 8797-8810.