Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $32.30 | Total: $161.50 |
| 1 | 10 | $27.36 | Total: $273.60 |
| 1 | 25 | $23.18 | Total: $579.50 |
| 1 | 50 | $19.76 | Total: $988.00 |
| 1 | 100 | $17.10 | Total: $1,710.00 |
Overview
AC-186 is a nonsteroidal estrogen receptor ? (ER?) agonist with different affinities for ER? and ER?, with an EC50 of 6 nM for ER? and 5000 nM for ER?. AC-186 has neuroprotective activity and has been used in the study of Parkinson's disease.
Chemical Properties
| Molecular Formula | C18H17F3O |
| Molecular Weight | 306.32 |
| CAS Numbers | 1421854-16-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | FC=1C=CC=CC1C2(C3=CC=C(O)C=C3)CCC(F)(F)CC2 |
Storage and Handling
0C Short Term, -20C Long Term
References
McFarland K, et al. AC-186, a selective nonsteroidal estrogen receptor ? agonist, shows gender specific neuroprotection in a Parkinson's disease rat model. ACS Chem Neurosci. 2013 Sep 18;4[9] 1249-55.