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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $84.15 | Total: $420.75 |
| 1 | 10 | $71.28 | Total: $712.80 |
| 1 | 25 | $60.39 | Total: $1,509.75 |
| 1 | 50 | $51.48 | Total: $2,574.00 |
| 1 | 100 | $44.55 | Total: $4,455.00 |
Overview
Giredestrant tartrate (Estrogen receptor antagonist 1) is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestrant tartrate strongly binds to ER, resulting in the failure of ER to activate the transcription of targeted genes and promoting the degradation of ER protein. Giredestrant tartrate can be used to treat tumor diseases.
Chemical Properties
| Molecular Formula | C31H37F5N4O7 |
| Molecular Weight | 672.64 |
| CAS Numbers | 2407529-33-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [C@@H]([C@H](C(O)=O)O)(C(O)=O)O.C(C(CO)(F)F)N1[C@@H](C2=C(C=3C(N2)=CC=CC3)C[C@H]1C)C4=C(F)C=C(NC5CN(CCCF)C5)C=C4F |
Storage and Handling
0C Short Term, -20C Long Term
References
Liang J, Zbieg JR, Blake RA, et al. GDC-9545 [Giredestrant] A Potent and Orally Bioavailable Selective Estrogen Receptor Antagonist and Degrader with an Exceptional Preclinical Profile for ER+ Breast Cancer. J Med Chem. 2021;64[16] 11841-11856.