Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $171.70 | Total: $858.50 |
| 1 | 10 | $145.44 | Total: $1,454.40 |
| 1 | 25 | $123.22 | Total: $3,080.50 |
| 1 | 50 | $105.04 | Total: $5,252.00 |
| 1 | 100 | $90.90 | Total: $9,090.00 |
Overview
GSK270822A is a selective ROCK1 inhibitor. GSK270822A exhibits IC50 of 9nM, 1100nM, 1550nM for ROCK1, RSK1, p70S6K, respectively.
Chemical Properties
| Molecular Formula | C24H20N4O2 |
| Molecular Weight | 396.44 |
| CAS Numbers | 864082-23-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(NC=1C=C2C(=CC1)NN=C2)(=O)C=3C(CC(=O)NC3C)C4=CC5=C(C=C4)C=CC=C5 |
Storage and Handling
0C Short Term, -20C Long Term
References
Identification and Structure-?Function Analysis of Subfamily Selective G Protein-?Coupled Receptor Kinase Inhibitors. By Homan, Kristoff T.; Larimore, Kelly M.; Elkins, Jonathan M.; Szklarz, Marta; Knapp, Stefan; Tesmer, John J. G. From ACS Chemical Biology [2015], 10[1], 310-319.