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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $45.90 | Total: $229.50 |
| 1 | 10 | $38.88 | Total: $388.80 |
| 1 | 25 | $32.94 | Total: $823.50 |
| 1 | 50 | $28.08 | Total: $1,404.00 |
| 1 | 100 | $24.30 | Total: $2,430.00 |
Overview
Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-?, PKC-?, PKC-?, PKC-?, and PKC-? with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory and antitumor activity.
Chemical Properties
| Molecular Formula | C25H34O6 |
| Molecular Weight | 430.53 |
| CAS Numbers | 75567-37-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC=C(C)C(=O)O[C@H]1C(C)=C[C@@]23[C@H](C)C[C@@H]4[C@H]([C@H](C=C(CO)[C@@H](O)[C@]12O)C3=O)C4(C)C |
Storage and Handling
0C Short Term, -20C Long Term
References
Ghoul A, et al. Epithelial-to-mesenchymal transition and resistance to ingenol 3-angelate, a novel protein kinase C modulator, in colon cancer cells. Cancer Res. 2009 May 15;69[10] 4260-9.