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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $28.90 | Total: $144.50 |
| 1 | 10 | $24.48 | Total: $244.80 |
| 1 | 25 | $20.74 | Total: $518.50 |
| 1 | 50 | $17.68 | Total: $884.00 |
| 1 | 100 | $15.30 | Total: $1,530.00 |
Overview
VPC-13566 is a BF3-specific small molecule, which effectively inhibited the androgen receptor transcriptional activity and displaced the BAG1L peptide from the BF3 pocket. VPC-13566 inhibits the growth of various prostate cancer cell lines and reduces the growth of AR-dependent prostate cancer xenograft tumors in mice.
Chemical Properties
| Molecular Formula | C18H14N2 |
| Molecular Weight | 258.32 |
| CAS Numbers | 218464-59-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC1=C2C(C(=CN2)C3=NC4=C(C=C3)C=CC=C4)=CC=C1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Lallous N, et al. Targeting Binding Function-3 of the Androgen Receptor Blocks Its Co-Chaperone Interactions, Nuclear Translocation, and Activation. Mol Cancer Ther. 2016 Dec;15[12] 2936-2945. Epub 2016 Oct 7.