Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $77.35 | Total: $386.75 |
| 1 | 10 | $65.52 | Total: $655.20 |
| 1 | 25 | $55.51 | Total: $1,387.75 |
| 1 | 50 | $47.32 | Total: $2,366.00 |
| 1 | 100 | $40.95 | Total: $4,095.00 |
Overview
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 ?M and 2 ?M).
Chemical Properties
| Molecular Formula | C25H44O3 |
| Molecular Weight | 392.62 |
| CAS Numbers | 1612191-86-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC[C@H]1[C@@H](O)[C@H]2[C@@H]3CC[C@H]([C@H](C)CCO)[C@@]3(C)CC[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |
Storage and Handling
0C Short Term, -20C Long Term
References
Festa C, et al. Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor [FXR] and G-protein coupled bile acid receptor 1 [GP-BAR1] ligands. J Med Chem. 2014 Oct 23;57[20] 8477-95.