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Overview
S-(2-aminoethyl) Isothiourea (dihydrobromide) is a non-selective inhibitor of all NOS isoforms. For human nNOS, eNOS, and iNOS, the Ki values are 1.8, 2.1, and 0.59 ?M, respectively
Chemical Properties
| Molecular Formula | C3H11Br2N3S |
| Molecular Weight | 281.02 |
| CAS Numbers | 56-10-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Br.Br.NCCSC(N)=N |
Storage and Handling
0C Short Term, -20C Long Term
References
Garvey E P , Oplinger J A , Tanoury G J , et al. Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas.[J]. Journal of Biological Chemistry, 1994, 269.