Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
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- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $37.40 | Total: $187.00 |
| 1 | 10 | $31.68 | Total: $316.80 |
| 1 | 25 | $26.84 | Total: $671.00 |
| 1 | 50 | $22.88 | Total: $1,144.00 |
| 1 | 100 | $19.80 | Total: $1,980.00 |
Overview
AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-? (TNF?), interferon-? (IFN-?), IL-10 and IL-17A.
Chemical Properties
| Molecular Formula | C21H23ClFNO2 |
| Molecular Weight | 375.87 |
| CAS Numbers | 1704801-24-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.COc1ccc2OCC(CN3CCCC3)=C(c3ccc(F)cc3)c2c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Borroto A, etal. First-in-class inhibitor of the T cell receptor for the treatment of autoimmune diseases. Sci Transl Med. 2016 Dec 21;8[370] 370ra184.