Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $124.95 | Total: $624.75 |
| 1 | 10 | $105.84 | Total: $1,058.40 |
| 1 | 25 | $89.67 | Total: $2,241.75 |
| 1 | 50 | $76.44 | Total: $3,822.00 |
| 1 | 100 | $66.15 | Total: $6,615.00 |
Overview
CDC801 is an inhibitor of PDE4 and TNF-? with IC50s of 1.1 ?M and 2.5 ?M, respectively.
Chemical Properties
| Molecular Formula | C23H24N2O5 |
| Molecular Weight | 408.45 |
| CAS Numbers | 192819-27-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(CC(N)=O)(N1C(=O)C=2C(C1=O)=CC=CC2)C3=CC(OC4CCCC4)=C(OC)C=C3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Man HW, et al. Discovery of [S]-N-[2-[1-[3-ethoxy-4-methoxyphenyl]-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl] acetamide [apremilast], a potent and orally active phosphodiesterase 4and tumor necrosis factor-alpha inhibitor. J Med Chem. 2009 Mar 26;52[6] 1522-4.