Pyrazoloacridine

Pyrazoloacridine

AT28475

CAS 99009-20-8

More details

1000 Items

$40.30

$40.30 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $26.35 Total: $131.75
110 $22.32 Total: $223.20
125 $18.91 Total: $472.75
150 $16.12 Total: $806.00
1100 $13.95 Total: $1,395.00

Overview

Pyrazoloacridine (PD 115934) is a nucleic acid binding agent that inhibits the activity of topo I and II with an IC50 of 1.25 ?M in K562 cells. Pyrazoloacridine shows anti-cancer activity.

Chemical Properties

Molecular FormulaC19H21N5O3
Molecular Weight367.4
CAS Numbers99009-20-8
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1ccc2[nH]c3c(ccc4n(CCCN(C)C)nc(c34)c2c1)[N+]([O-])=O

Storage and Handling

0C Short Term, -20C Long Term

References

Chen DS, et al. Combinatorial synthesis of pyrazoloquinoline and pyrazoloacridine derivatives with high regioselectivity. Comb Chem High Throughput Screen. 2013 Jun 28;16[7] 550-61.