Coralyne chloride

Coralyne chloride

AT31011

CAS 38989-38-7

More details

1000 Items

$35.10

$35.10 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $22.95 Total: $114.75
110 $19.44 Total: $194.40
125 $16.47 Total: $411.75
150 $14.04 Total: $702.00
1100 $12.15 Total: $1,215.00

Overview

Coralyne chloride is a protoberberine with strong anticancer activity. It can be used to prepare Coralyne derivatives, a fluorescent DNA-based molecular rectifier built into DNA duplexes through site-specific insertion. It acts as a topoisomerase I toxic molecule, inducing topoisomerase I-mediated DNA cleavage.

Chemical Properties

Molecular FormulaC22H22ClNO4
Molecular Weight399.87
CAS Numbers38989-38-7
SolubilityDMSO
Purity98% by HPLC
SMILES Code[Cl-].COc1cc2cc[n+]3c(C)c4cc(OC)c(OC)cc4cc3c2cc1OC

Storage and Handling

0C Short Term, -20C Long Term

References

Khadka DB, Cho WJ. Topoisomerase inhibitors as anticancer agents a patent update. Expert Opin Ther Pat. 2013 Aug;23[8] 1033-56.