Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- Cytokine Receptors
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- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
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- PET/SPECT Imaging Precursors
- Customized Screening Library
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- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
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- Molecular Glues
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $89.25 | Total: $446.25 |
| 1 | 10 | $75.60 | Total: $756.00 |
| 1 | 25 | $64.05 | Total: $1,601.25 |
| 1 | 50 | $54.60 | Total: $2,730.00 |
| 1 | 100 | $47.25 | Total: $4,725.00 |
Overview
(4-NH2)-Exatecan is a topoisomerase inhibitor with potential anticancer activity for the synthesis of antibody drug conjugates (ADCs).
Chemical Properties
| Molecular Formula | C23H21N3O4 |
| Molecular Weight | 403.43 |
| CAS Numbers | 2495742-21-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccc(N)c5CCCc(c3Cn1c2=O)c45 |
Storage and Handling
0C Short Term, -20C Long Term
References
Sugimori M,et al. Synthesis and antitumor activity of ring A- and F-modified hexacyclic camptothecin analogues. J Med Chem. 1998 Jun 18;41[13] 2308-18.