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NRX-252114
AOB17866
CAS: N/A
Chemical Name: 2-(4-((2,6-Dichlorophenyl)thio)-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carbonyl)isoindoline-4-carbonitrile
1929 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $41.65 | Total: $208.25 |
| 1 | 10 | $35.28 | Total: $352.80 |
| 1 | 25 | $29.89 | Total: $747.25 |
| 1 | 50 | $25.48 | Total: $1,274.00 |
| 1 | 100 | $22.05 | Total: $2,205.00 |
Overview
Novel potent enhancer of the interaction between an oncogenic transcription factor, β-Catenin, and its cognate E3 ligase, SCFβ-TrCP
Chemical Properties
| Molecular Formula | C22H12Cl2F3N3O2S |
| Molecular Weight | 510.31 |
| Solubility | DMSO and Alcohol |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 2-(4-((2,6-Dichlorophenyl)thio)-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carbonyl)isoindoline-4-carbonitrile |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
1) Kyle R. Simonetta, et al., Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction, Nature Communications volume 10, Article number: 1402 (2019)
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