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Cantharidin
AOB34277
CAS : 56-25-7
Chemical Name: (3aR,4S,7R,7aS)-3a,7a-Dimethylhexahydro-4,7-epoxyisobenzofuran-1,3-dione
994 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | 20mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $26.35 | Total: $131.75 |
| 1 | 10 | $22.32 | Total: $223.20 |
| 1 | 25 | $18.91 | Total: $472.75 |
| 1 | 50 | $16.12 | Total: $806.00 |
| 1 | 100 | $13.95 | Total: $1,395.00 |
Overview
Natural inhibitor of HSF1 transcriptional activity; Potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A), altering GPI-anchored protein sorting by targeting Cdc1-mediated remodeling in endoplasmic reticulum
Chemical Properties
| Molecular Formula | C10H12O4 |
| CAS Numbers | 56-25-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (3aR,4S,7R,7aS)-3a,7a-Dimethylhexahydro-4,7-epoxyisobenzofuran-1,3-dione |
| InChl Key | DHZBEENLJMYSHQ-XCVPVQRUSA-N |
| InChl Code | InChI=1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10- |
| SMILES Code | O=C1OC([C@]2(C)[C@H]3CC[C@H](O3)[C@@]21C)=O |
Synonyms
NSC 61805
References
1) Honkanen, R.E. Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A. FEBS Lett. 330(3), 283-286 (1993).
2) McCluskey, A., Sim, A.T.R., and Sakoff, J.A. Serine-threonine protein phosphatase inhibitors: Development of potential therapeutic strategies. J. Med. Chem. 45(6), 1151-1175 (2002).