AT 14 acetate

AT 14 acetate

ATP2109L

1000 Items

$184.60

$184.60 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $120.70 Total: $603.50
110 $102.24 Total: $1,022.40
125 $86.62 Total: $2,165.50
150 $73.84 Total: $3,692.00
1100 $63.90 Total: $6,390.00

Overview

TAT 14 acetate, a 14-mer peptide, is an Nrf2 activator with anti-inflammatory properties. TAT 14 acetate increases Nrf2 protein levels due to targeting the Nrf2 binding site on Keap1, but has no effect on Nrf2 mRNA expression.

Chemical Properties

Molecular FormulaC139H234N48O41
Molecular Weight3233.64
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(O)=O.O=C(N)CC[C@@H](C(O)=O)NC([C@H]([C@@H](C)CC)NC([C@H]1N(C([C@H](CC(C)C)NC([C@H](CC2=CC=CC=C2)NC([C@H](CCC(O)=O)NC(CNC([C@H]([C@H](O)C)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](CC3=CC=C(O)C=C3)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC1)=O)=O

Storage and Handling

0C Short Term, -20C Long Term

References

Richard Steel, et al. Anti-inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2Keap1 Interaction. ACS Med Chem Lett. 2012 May 10;3[5] 407-410.