Ibiglustat

Ibiglustat

AT4473

CAS 1401090-53-6

More details

1000 Items

$61.10

$61.10 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $39.95 Total: $199.75
110 $33.84 Total: $338.40
125 $28.67 Total: $716.75
150 $24.44 Total: $1,222.00
1100 $21.15 Total: $2,115.00

Overview

Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthesis of GL-3. Ibiglustat is potentially useful for treating Fabry disease. Fabry disease is a rare lysosomal storage disorder, which results in abnormal tissue deposits of a particular fatty substance called globotriaosylceramide (GL-3 or Gb3) throughout the body.

Chemical Properties

Molecular FormulaC20H24FN3O2S
Molecular Weight389.49
CAS Numbers1401090-53-6
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(C)(NC(=O)O[C@@H]1CN2CCC1CC2)c1csc(n1)-c1ccc(F)cc1

Storage and Handling

0C Short Term, -20C Long Term

References

Schiffmann R, et al. Fabry disease. Handb Clin Neurol. 2015;132 231-48.