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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $34.00 | Total: $170.00 |
| 1 | 10 | $28.80 | Total: $288.00 |
| 1 | 25 | $24.40 | Total: $610.00 |
| 1 | 50 | $20.80 | Total: $1,040.00 |
| 1 | 100 | $18.00 | Total: $1,800.00 |
Overview
HBX 41108 (HBX-41108) is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBX 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8?M.
Chemical Properties
| Molecular Formula | C13H3ClN4O |
| Molecular Weight | 266.64 |
| CAS Numbers | 924296-39-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Clc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N |
Storage and Handling
0C Short Term, -20C Long Term
References
Colland F, Formstecher E, Jacq X, et al. Small-molecule inhibitor of USP7HAUSP ubiquitin protease stabilizes and activates p53 in cells. Mol Cancer Ther, 2009, 8[8] 2286-2295.