USP30 inhibitor 18

USP30 inhibitor 18

AT36682

CAS 2242582-40-5

More details

1000 Items

$162.50

$162.50 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $106.25 Total: $531.25
110 $90.00 Total: $900.00
125 $76.25 Total: $1,906.25
150 $65.00 Total: $3,250.00
1100 $56.25 Total: $5,625.00

Overview

USP30 inhibitor 18 is a selective inhibitor of USP30 (IC50 = 0.02 ?M). USP30 inhibitor 18 is able to accelerate mitophagy and increase protein ubiquitination.

Chemical Properties

Molecular FormulaC26H28FN3O4S
Molecular Weight497.58
CAS Numbers2242582-40-5
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)c2ccc(F)cc2)cc1

Storage and Handling

0C Short Term, -20C Long Term

References

Arthur F Kluge, et al. Novel highly selective inhibitors of ubiquitin specific protease 30 [USP30] accelerate mitophagy. Bioorg Med Chem Lett. 2018 Aug 15;28[15] 2655-2659.