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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
USP8-IN-3 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with IC50 of 4.0 ?M against USP8D. USP8-IN-3 inhibited the proliferation of GH3 and H1957 cells with GI50 values of 37.03 ?M and 6.01 ?M, respectively. USP8-IN-3 is a potential compound for the treatment of cancer and viral infections.
Chemical Properties
| Molecular Formula | C18H18F3N5O2S |
| Molecular Weight | 425.43 |
| CAS Numbers | 2477651-10-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(F)(F)(F)C1=NC(=CC=C1)N2CCC(NC(NC3=CC=C(N(=O)=O)C=C3)=S)CC2 |
Storage and Handling
0C Short Term, -20C Long Term
References
Li zhiyun, et al. Preparing method and application of USP8 inhibitor China, CN111138358 A. 2020-05-12