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Doxorubicin hydrochloride
AOB5216
CAS No:25316-40-9
Chemical Name: Adriamycin
454 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $9.35 | Total: $46.75 |
| 1 | 10 | $7.92 | Total: $79.20 |
| 1 | 25 | $6.71 | Total: $167.75 |
| 1 | 50 | $5.72 | Total: $286.00 |
| 1 | 100 | $4.95 | Total: $495.00 |
Overview
An anthracycline antibiotic with antineoplastic activity
References:
1. Liu YY, Gupta V, Patwardhan GA, Bhinge K, Zhao Y, Bao J, Mehendale H, Cabot MC, Li YT, Jazwinski SM. Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and beta-catenin signaling. Mol Cancer. 2010 Jun 11;9(1):145. [Epub ahead of print] PubMed PMID: 20540746.
2. Zaremba T, Thomas H, Cole M, Plummer ER, Curtin NJ. Doxorubicin-induced suppression of poly(ADP-ribose) polymerase-1 (PARP-1) activity and expression and its implication for PARP inhibitors in clinical trials. Cancer Chemother Pharmacol. 2010 May 21. [Epub ahead of print] PubMed PMID: 20490796.
3. Angelini A, Di Ilio C, Castellani ML, Conti P, Cuccurullo F. Modulation of multidrug resistance p-glycoprotein activity by flavonoids and honokiol in human doxorubicin- resistant sarcoma cells (MES-SA/DX-5): implications for natural sedatives as chemosensitizing agents in cancer therapy. J Biol Regul Homeost Agents. 2010 Apr-Jun;24(2):197-205. PubMed PMID: 20487633.
Chemical Properties
| Molecular Formula | C27H29NO11 HCl |
| Molecular Weight | 543.52 |
| CAS Numbers | 25316-40-9 |
| Solubility | DMSO |
| Purity | 99% (HPLC) |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
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