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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the Treatment of Migraine.
Chemical Properties
| Molecular Formula | C20H12F5N3O4 |
| Molecular Weight | 453.32 |
| CAS Numbers | 1416799-28-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | OC(=O)c1ccc(nc1)C(=O)N[C@@H](c1ccc(OC(F)(F)F)c(F)c1)c1ncccc1F |
Storage and Handling
0C Short Term, -20C Long Term
References
Horne DB, et al. Discovery of TRPM8 Antagonist [ S]-6-[[[3-Fluoro-4-[trifluoromethoxy]phenyl][3-fluoropyridin-2-yl]methyl]carbamoyl]nicotinic Acid [AMG 333], a Clinical Candidate for the Treatment of Migraine. J Med Chem. 2018 Sep 27;61[18] 8186-8201.