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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $96.05 | Total: $480.25 |
| 1 | 10 | $81.36 | Total: $813.60 |
| 1 | 25 | $68.93 | Total: $1,723.25 |
| 1 | 50 | $58.76 | Total: $2,938.00 |
| 1 | 100 | $50.85 | Total: $5,085.00 |
Overview
PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.
Chemical Properties
| Molecular Formula | C19H10ClF4N5O3S2 |
| Molecular Weight | 531.89 |
| CAS Numbers | 1235406-03-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(C1=C(C=C(C(F)(F)F)C=C1)C=2C=CN=NC2)C3=C(Cl)C=C(S(NC4=NN=CS4)(=O)=O)C(F)=C3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Hannah M Jones , Richard P Butt , Rob W Webster,et al.Clinical Micro-Dose Studies to Explore the Human Pharmacokinetics of Four Selective Inhibitors of Human Nav1.7 Voltage-Dependent Sodium Channels.Clin Pharmacokinet. 2016 Jul;55[7] 875-887.