Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
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- Nuclear Receptor Ligands
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $28.05 | Total: $140.25 |
| 1 | 10 | $23.76 | Total: $237.60 |
| 1 | 25 | $20.13 | Total: $503.25 |
| 1 | 50 | $17.16 | Total: $858.00 |
| 1 | 100 | $14.85 | Total: $1,485.00 |
Overview
RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.
Chemical Properties
| Molecular Formula | C21H23F3N4O5S |
| Molecular Weight | 500.49 |
| CAS Numbers | 1803003-68-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(NC1=CC=C(S(=O)(=O)N2CCN(C(C)C)CC2)C=C1)(=O)C3=C(N(=O)=O)C=C(C(F)(F)F)C=C3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Wei ZL, et al. Identification of orally-bioavailable antagonists of the TRPV4 ion-channel. Bioorg Med Chem Lett. 2015 Sep 15;25[18] 4011-5.