NaV1.7 inhibitor-1

NaV1.7 inhibitor-1

AT12181

CAS 1494585-79-3

More details

1000 Items

$117.00

$117.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $76.50 Total: $382.50
110 $64.80 Total: $648.00
125 $54.90 Total: $1,372.50
150 $46.80 Total: $2,340.00
1100 $40.50 Total: $4,050.00

Overview

NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).

Chemical Properties

Molecular FormulaC23H30FNO4S
Molecular Weight435.55
CAS Numbers1494585-79-3
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC1(COc2cc(F)c(cc2C2CC2)C(=O)NS(=O)(=O)C2CC2)CCC2(CC2)CC1

Storage and Handling

0C Short Term, -20C Long Term

References

Sun S, Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-GatedSodium Channel [NaV] 1.7 with Potent Analgesic Activity. J Med Chem. 2019 Jan 24;62[2] 908-927.