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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $48.45 | Total: $242.25 |
| 1 | 10 | $41.04 | Total: $410.40 |
| 1 | 25 | $34.77 | Total: $869.25 |
| 1 | 50 | $29.64 | Total: $1,482.00 |
| 1 | 100 | $25.65 | Total: $2,565.00 |
Overview
MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1), with Ki values of 11.4 nM and 23.8 nM for hTRPV1 and rTRPV1, respectively, and EC50s of 5.05 nM and 93 nM for hTRPV1 and rTRPV1, respectively. MDR-652 is a potent topical analgesic.
Chemical Properties
| Molecular Formula | C22H23ClFN3O2S |
| Molecular Weight | 447.95 |
| CAS Numbers | 1933528-96-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)(C)c1nc(c(CNC(=O)Nc2ccc(CO)c(F)c2)s1)-c1cccc(Cl)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Jihyae Ann, et al. Discovery of Nonpungent Transient Receptor Potential Vanilloid 1 [TRPV1] Agonist as Strong Topical Analgesic. J Med Chem. 2020 Jan 9;63[1] 418-424.