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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $513.40 | Total: $2,567.00 |
| 1 | 10 | $434.88 | Total: $4,348.80 |
| 1 | 25 | $368.44 | Total: $9,211.00 |
| 1 | 50 | $314.08 | Total: $15,704.00 |
| 1 | 100 | $271.80 | Total: $27,180.01 |
Overview
D-GsMTx4 TFA, a selective spider venom peptide, is a TRPC16 and Piezo2 inhibitor that inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families, blocks cation-selective stretch-activated channels (SACs), and attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglia reactivity. toxicity and microglia reactivity.D-GsMTx4 TFA prevented myocardial infarction in a mouse model of ischemiareperfusion and can be used to characterize the role of excitatory MSCs in normal physiology and pathology.
Chemical Properties
| Molecular Formula | C187H279F3N48O48S6 |
| Molecular Weight | 4217 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
Storage and Handling
0C Short Term, -20C Long Term
References
Alcaino C, et al. Mechanosensitive ion channel Piezo2 is inhibited by D-GsMTx4. Channels [Austin]. 2017 May 4;11[3] 245-253.