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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $107.10 | Total: $535.50 |
| 1 | 10 | $90.72 | Total: $907.20 |
| 1 | 25 | $76.86 | Total: $1,921.50 |
| 1 | 50 | $65.52 | Total: $3,276.00 |
| 1 | 100 | $56.70 | Total: $5,670.00 |
Overview
GNE-131 is a potent and specific inhibitor of human sodium channel NaV1.7 (IC50: 3 nM).
Chemical Properties
| Molecular Formula | C23H30N4O3S |
| Molecular Weight | 442.57 |
| CAS Numbers | 1629063-81-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=S(=O)(Nc1nnc2cc(OCC34CC5CC(CC(C5)C3)C4)c(cn12)C1CC1)C1CC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Focken T, et al. Design of Conformationally Constrained Acyl Sulfonamide Isosteres Identification of N-[[1,2,4]Triazolo[4,3- a]pyridin-3-yl]methane-sulfonamides as Potent and Selective hNaV1.7 Inhibitors for the Treatment of Pain. J Med Chem. 2018 Jun 14;61[11] 4810-4831.