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Overview
TRPM8 antagonist WS-3 (Cyclohexanecarboxamide) is an agonist of TRPM8( EC50 : 3.7 ?M).
Chemical Properties
| Molecular Formula | C13H25NO |
| Molecular Weight | 211.34 |
| CAS Numbers | 39711-79-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(NCC)(=O)C1C(C(C)C)CCC(C)C1 |
Storage and Handling
0C Short Term, -20C Long Term
References
H?J Behrendt, Germann T , Gillen C , et al. Characterization of the mouse cold?menthol receptor TRPM8 and vanilloid receptor type?1 VR1 using a fluorometric imaging plate reader [FLIPR] assay[J]. British Journal of Pharmacology, 2004, 141[4].