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BMS-1001 hydrochloride View larger

BMS-1001 hydrochloride

AOB31743

CAS No: 2113650-04-5

 

Chemical Name: (2-((3-Cyanobenzyl)oxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)-5-methylbenzyl)-D-serine hydrochloride

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$37.50

$37.50 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $31.88 Total: $159.38
110 $27.00 Total: $270.00
125 $22.88 Total: $571.88
150 $19.50 Total: $975.00
1100 $16.88 Total: $1,687.50

Data sheet

Molecular FormulaC35H35ClN2O7
Molecular Weight631.12
CAS Numbers2113650-04-5
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymBMS-1001 HCl; BMS 1001 HCl; BMS1001 HCl; BMS-1001 hydrochloride; BMS 1001 hydrochloride; BMS1001 hydrochloride
IUPAC/Chemical Name(2-((3-Cyanobenzyl)oxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)-5-methylbenzyl)-D-serine hydrochloride
InChl KeyVKDUZONDVBDCAX-VNUFCWELSA-N
InChl CodeInChI=1S/C35H34N2O7.ClH/c1-22-13-28(18-37-30(19-38)35(39)40)33(43-20-25-6-3-5-24(14-25)17-36)16-32(22)44-21-27-7-4-8-29(23(27)2)26-9-10-31-34(15-26)42-12-11-41-31;/h3-10,13-16,30,37-38H,11-12,18-21H2,1-2H3,(H,39,40);1H/t30-;/m1./s1
SMILES CodeOC[C@H](C(O)=O)NCC1=CC(C)=C(OCC2=CC=CC(C3=CC=C4OCCOC4=C3)= C2C)C=C1OCC5=CC=CC(C#N)=C5.[H]Cl
ReferencesSkalniak L, Zak KM, Guzik K, Magiera K, Musielak B, Pachota M, Szelazek B, Kocik J, Grudnik P, Tomala M, Krzanik S, Pyrc K, Dömling A, Dubin G, Holak TA. Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells. Oncotarget. 2017 Aug 7;8(42):72167-72181

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