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STING-agonist-C11
AOB33283
CAS No: 875863-22-2
Chemical Name: C11; N-(Methylcarbamoyl)-2-{[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-2-phenylacetamide
834 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $36.55 | Total: $182.75 |
| 1 | 10 | $30.96 | Total: $309.60 |
| 1 | 25 | $26.23 | Total: $655.75 |
| 1 | 50 | $22.36 | Total: $1,118.00 |
| 1 | 100 | $19.35 | Total: $1,935.00 |
Overview
Novel agonist of the STING pathway, inducing IFN secretion from human cells, activating the type I IFN response in a manner that requires the adaptor protein STING but not alternative adaptors MAVS and TRIF, depending on signaling through STING to produce antiviral type I interferon
Chemical Properties
| Molecular Formula | C19H18N4O3S |
| Molecular Weight | 382.44 |
| CAS Numbers | 875863-22-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | N-(Methylcarbamoyl)-2-{[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-2-phenylacetamide |
| InChl Key | KQKWXSQTTDLZSO-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C19H18N4O3S/c1-12-8-10-14(11-9-12)17-22-23-19(26-17)27-15(13-6-4-3-5-7-13)16(24)21-18(25)20-2/h3-11,15H,1-2H3,(H2,20,21,24,25) |
| SMILES Code | O=C(NC(NC)=O)C(SC1=NN=C(C2=CC=C(C)C=C2)O1)C3=CC=CC=C3 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
STING-agonist-C11; STINGagonistC11; STING agonist C11; STING agonist-C11; C11; C-11; C 11
References
Gall, B., Pryke, K., Abraham, J., et al. Emerging alphaviruses are sensitive to cellular states induced by a novel small-molecule agonist of the STING pathway. J. Virol. 92(6), e01913-01917 (2018)
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