Enzyme Inhibitors

JMS-053 View larger

JMS-053

AOB31947

CAS: 1954650-11-3

 

Chemical Name: JMS-631-053; 7-Imino-2-phenylthieno[3,2-c]pyridine-4,6(5H,7H)-dione

AOBIOUS launched this product in 2019

CITATIONS - Publications That Use AOBIOUS Product

1) Sci Rep. 2020; 10: 12879.

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Molarity Calculation Cart®

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$119.00

$119.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $53.55 Total: $5,355.00
150 $61.88 Total: $3,094.00
125 $72.59 Total: $1,814.75
110 $85.68 Total: $856.80
15 $101.15 Total: $505.75

Data sheet

Molecular FormulaC13H8N2O2S
Molecular Weight256.28
CAS Numbers1954650-11-3
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO and Water
Purity 99% (HPLC)
SynonymJMS-631-053; JMS053; JMS 053; JMS-053
IUPAC/Chemical Name7-Imino-2-phenylthieno[3,2-c]pyridine-4,6(5H,7H)-dione
InChl KeyCQHAROORCYWRRH-UHFFFAOYSA-N
InChl CodeInChI=1S/C13H8N2O2S/c14-10-11-8(12(16)15-13(10)17)6-9(18-11)7-4-2-1-3-5-7/h1-6,14H,(H,15,16,17)
SMILES Code O=C1C(C=C(C2=CC=CC=C2)S3)=C3C(C(N1)=O)=N
References1) McQueeney KE etc. Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitor, Oncotarget. 2017 Dec 30;9(9):8223-8240

2) Sharon R etc. The Mechanism of Inhibition of the Undrugged Oncogenic Phosphatase PTP4A3 by a Novel Small Molecule JMS-053, FASEB Journal Vol. 33, No. 1 April 2019

More info

Novel allosteric PTP4A3 inhibitor, increasing Emilin 1 gene expression

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