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UNC1062
AOB4488
CAS No: 1350549-36-8
Chemical Name:4-[6-(Butylamino)-3-[4-(4-morpholinylsulfonyl)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-cyclohexanol
AOBIOUS launched this product in 2013
CITATIONS - Publications That Use AOBIOUS Product
282 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $45.05 | Total: $225.25 |
| 1 | 10 | $38.16 | Total: $381.60 |
| 1 | 25 | $32.33 | Total: $808.25 |
| 1 | 50 | $27.56 | Total: $1,378.00 |
| 1 | 100 | $23.85 | Total: $2,385.00 |
Overview
Novel MERTK-selective tyrosine kinase inhibitor
====================================
Citation (Publications used AOBIOUS products)
2) Dissertation (2015) - Entwicklung neuer Therapien in Tumoren des Kopf-Hals Bereichs
Chemical Properties
| Molecular Formula | C25H34N6O4S |
| Molecular Weight | 514.64 |
| CAS Numbers | 1350549-36-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 4-[6-(butylamino)-3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]cyclohexan-1-ol |
| InChl Key | KAAPXWSYROPAEL-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C25H34N6O4S/c1-2-3-12-26-25-27-17-22-23(29-31(24(22)28-25)19-6-8-20(32)9-7-19)18-4-10-21(11-5-18)36(33,34)30-13-15-35-16-14-30/h4-5,10-11,17,19-20,32H,2-3,6-9,12-16H2,1H3,(H,26,27,28) |
| SMILES Code | CCCCNC1=NC=C2C(=NN(C2=N1)C3CCC(CC3)O)C4=CC=C(C=C4)S(=O)(=O)N5CCOCC5 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
1) Schlegel J, et al. J Clin Invest. 123(5):2257-67 (2013).
2) Liu J, et al. Eur J Med Chem. 65:83-93 (2013).
3) von Mässenhausen A, et al. Oncotarget. 7(22):32678-94 (2016).
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