GDNF Receptors

NecroX-7 View larger

NecroX-7

AOB17286

CAS: 1120333-38-1

Chemical Name: 4-((7-((1-(Methylsulfonyl)piperidin-4-yl)amino)-2-phenyl-1H-indol-5-yl)methyl)thiomorpholine 1,1-dioxide

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$37.00

$37.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $16.65 Total: $1,665.00
50 $19.24 Total: $962.00
25 $22.57 Total: $564.25
10 $26.64 Total: $266.40
5 $31.45 Total: $157.25

Data sheet

Molecular FormulaC25H32N4O4S2
Molecular Weight516.68
CAS Numbers1120333-38-1
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity95% by HPLC
SynonymNecroX-7; NecroX 7; NecroX7
IUPAC/Chemical Name4-((7-((1-(Methylsulfonyl)piperidin-4-yl)amino)-2-phenyl-1H-indol-5-yl)methyl)thiomorpholine 1,1-dioxide
InChl KeyOXROWZRDUZOTSG-UHFFFAOYSA-N
InChl CodeInChI=1S/C25H32N4O4S2/c1-34(30,31)29-9-7-22(8-10-29)26-24-16-19(18-28-11-13-35(32,33)14-12-28)15-21-17-23(27-25(21)24)20-5-3-2-4-6-20/h2-6,15-17,22,26-27H,7-14,18H2,1H3
SMILES CodeO=S(N1CCC(NC2=CC(CN3CCS(CC3)(=O)=O)=CC4=C2NC(C5=CC=CC=C5)=C4)CC1)(C)=O
References1) Im KI, Nam YS, Kim N, Song Y, Lee ES, Lim JY, Jeon YW, Cho SG. Regulation of HMGB1 release protects chemoradiotherapy-associated mucositis. Mucosal Immunol. 2019 Jan 15.

2) Hwang IC, Kim JY, Kim JH, Lee JE, Seo JY, Lee JW, Park J, Yang HM, Kim SH, Cho HJ, Kim HS. Therapeutic Potential of a Novel Necrosis Inhibitor, 7-Amino-Indole, in Myocardial Ischemia-Reperfusion Injury. Hypertension. 2018 Jun;71(6):1143-1155. doi: 10.1161/HYPERTENSIONAHA.117.09405. Epub 2018 Apr 16. PubMed PMID: 29661840; PubMed Central PMCID: PMC5959205.

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