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AOB33070
CAS: 1425944-22-4 (free base)
Chemical Name: 2-(2-((2-nitro-9H-fluoren-9-ylidene)methyl)phenoxy)ethan-1-amine
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Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
---|---|---|---|
1 | 100 | $16.65 | Total: $1,665.00 |
1 | 50 | $19.24 | Total: $962.00 |
1 | 25 | $22.57 | Total: $564.25 |
1 | 10 | $26.64 | Total: $266.40 |
1 | 5 | $31.45 | Total: $157.25 |
Molecular Formula | C24H19F3N2O5 |
Molecular Weight | 472.42 |
CAS Numbers | 1425944-22-4 (free base) |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO |
Purity | 98% by HPLC |
Synonym | CYD-2-11; CYD 2 11; CYD211 |
IUPAC/Chemical Name | (E)-2-(2-((2-nitro-9H-fluoren-9-ylidene)methyl)phenoxy)ethan-1-amine |
InChl Key | BJIFXXDQMBHYKG-DEDYPNTBSA-N |
InChl Code | InChI=1S/C22H18N2O3/c23-11-12-27-22-8-4-1-5-15(22)13-20-18-7-3-2-6-17(18)19-10-9-16(24(25)26)14-21(19)20/h1-10,13-14H,11-12,23H2/b20-13+ |
SMILES Code | NCCOC1=CC=CC=C1/C=C2C3=C(C4=C/2C=CC=C4)C=CC([N+]([O-])=O)=C3 |
References | Li R, Ding C, Zhang J, Xie M, Park D, Ding Y, Chen G, Zhang G, Gilbert-Ross M, Zhou W, Marcus AI, Sun SY, Chen ZG, Sica GL, Ramalingam SS, Magis AT, Fu H, Khuri FR, Curran WJ, Owonikoko TK, Shin DM, Zhou J, Deng X. Modulation of Bax and mTOR for Cancer Therapeutics. Cancer Res. 2017 Jun 1;77(11):3001-3012. |
Novel potent and selective Bax agonist, targeting the structural pocket proximal to S184 in the C-terminal region of Bax