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iGOT1-01
AOB17797
CAS No: 882256-55-5
Chemical Name: 4-(1H-Indol-4-yl)-N-phenylpiperazine-1-carboxamide
984 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $50.15 | Total: $250.75 |
| 1 | 10 | $42.48 | Total: $424.80 |
| 1 | 25 | $35.99 | Total: $899.75 |
| 1 | 50 | $30.68 | Total: $1,534.00 |
| 1 | 100 | $26.55 | Total: $2,655.00 |
Overview
A novel inhibitor of aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1, GOT1)
Chemical Properties
| Molecular Formula | C19H20N4O |
| Molecular Weight | 320.40 |
| CAS Numbers | 882256-55-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 4-(1H-Indol-4-yl)-N-phenylpiperazine-1-carboxamide |
| InChl Key | MGSDOEMLWKEWSV-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C19H20N4O/c24-19(21-15-5-2-1-3-6-15)23-13-11-22(12-14-23)18-8-4-7-17-16(18)9-10-20-17/h1-10,20H,11-14H2,(H,21,24) |
| SMILES Code | O=C(N1CCN(C2=CC=CC3=C2C=CN3)CC1)NC4=CC=CC=C4 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
iGOT101; iGOT1 01; iGOT1-01
References
Holt MC, Assar Z, Beheshti Zavareh R, Lin L, Anglin J, Mashadova O, Haldar D, Mullarky E, Kremer DM, Cantley LC, Kimmelman AC, Stein AJ, Lairson LL, Lyssiotis CA. Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors. Biochemistry. 2018 Nov 27;57(47):6604-6614