GSK3987 (LXRα/β Agonist)

Name: GSK3987 (LXRα/β Agonist)
Brand: AOBIOUS
SKU: AOB8048
Price: 49 USD
Availability: InStock

Cat No: AOB8048

Condition

CAS: 264206-85-1

Chemical Name: 1-Benzyl-3-(4-methoxyanilino)-4-phenylpyrrole-2,5-dione

More details

1992 Item Items

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Quantity Discount Table - Order More To Get More Price Discount

Quantity	mg	Unit Price ($/mg or $/Unit)	Final Price
1	5	$41.65	Total: $208.25
1	10	$35.28	Total: $352.80
1	25	$29.89	Total: $747.25
1	50	$25.48	Total: $1,274.00
1	100	$22.05	Total: $2,205.00

Overview

Potent and specific liver X receptor (LXR) dual agonist of LXRalpha and LXRbeta

Chemical Properties

Molecular Formula	C24H20N2O3
Molecular Weight	384.44
CAS Numbers	264206-85-1
Solubility	DMSO
Purity	98% by HPLC
IUPAC/Chemical Name	1-Benzyl-3-(4-methoxyanilino)-4-phenylpyrrole-2,5-dione
InChl Key	HLZMYWLMBBLASX-UHFFFAOYSA-N
InChl Code	InChI=1S/C24H20N2O3/c1-29-20-14-12-19(13-15-20)25-22-21(18-10-6-3-7-11-18)23(27)26(24(22)28)16-17-8-4-2-5-9-17/h2-15,25H,16H2,1H3
SMILES Code	O=C(C(NC1=CC=C(OC)C=C1)=C2C3=CC=CC=C3)N(CC4=CC=CC=C4)C2=O

Storage and Handling

0°C (short term), -20°C (long term), desiccated

Synonyms

GSK3987; LXRα/β Agonist

References

1) Ranganathan PV, et al., Netrin-1-treated macrophages protect the kidney against ischemia-reperfusion injury and suppress inflammation by inducing M2 polarization. Am J Physiol Renal Physiol. 2013 Apr 1;304(7):F948-57.

2) Lin HR. Paeoniflorin acts as a liver X receptor agonist. J Asian Nat Prod Res. 2013;15(1):35-45. doi: 10.1080/10286020.2012.742510. Epub 2013 Jan 3. PubMed PMID: 23281636.

3) Jaye MC, et al. Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structure. J Med Chem. 2005 Aug 25;48(17):5419-22. PubMed PMID: 16107141.