R406

R406

AOB87473

494 Items

$13.00

$13.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $8.50 Total: $42.50
110 $7.20 Total: $72.00
125 $6.10 Total: $152.50
150 $5.20 Total: $260.00
1100 $4.50 Total: $450.00

Chemical Properties

Molecular FormulaC22H23FN6O5
Molecular Weight470.45
CAS Numbers841290-80-0
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name6-[[5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one
InChl KeyNHHQJBCNYHBUSI-UHFFFAOYSA-N
InChl CodeInChI=1S/C22H23FN6O5/c1-22(2)20(30)28-19-13(34-22)6-7-16(27-19)26-18-12(23)10-24-21(29-18)25-11-8-14(31-3)17(33-5)15(9-11)32-4/h6-10H,1-5H3,(H3,24,25,26,27,28,29,30)
SMILES CodeCOC1=C(OC)C=C(NC2=NC(NC3=NC(NC(C(C)(C)O4)=O)=C4C=C3)=C(F)C=N2)C=C1OC

Storage and Handling

0°C (short term), -20°C (long term), desiccated

Synonyms

R 406, R406, R-406, Tamatinib

References

1) Matsubara, S., Li, G., Takeda, K., et al. Inhibition of spleen tyrosine kinase prevents mast cell activation and airway hyperresponsiveness. American Journal of Respiration and Critical Care Medicine 173(1), 56-63 (2006).

2) Matsubara, S., Koya, T., Takeda, K., et al. Syk activation in dendritic cells is essential for airway hyperresponsiveness and inflammation. Am. J. Respir. Cell Mol. Biol. 34(4), 426-433 (2006).

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