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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $8.50 | Total: $42.50 |
| 1 | 10 | $7.20 | Total: $72.00 |
| 1 | 25 | $6.10 | Total: $152.50 |
| 1 | 50 | $5.20 | Total: $260.00 |
| 1 | 100 | $4.50 | Total: $450.00 |
Chemical Properties
| Molecular Formula | C27H25ClFN3O |
| Molecular Weight | 461.97 |
| CAS Numbers | 215303-72-3 (Free Base) |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 4-[4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol hydrochloride |
| InChl Key | QSUSKMBNZQHHPA-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C27H24FN3O/c28-24-13-11-22(12-14-24)26-27(23-15-17-29-18-16-23)31(25(30-26)10-4-5-20-32)19-6-9-21-7-2-1-3-8-21/h1-3,7-8,11-18,32H,5-6,9,19-20H2 |
| SMILES Code | FC(C=C1)=CC=C1C2=C(C3=CC=NC=C3)N(CCCC4=CC=CC=C4)C(C#CCCO)=N2 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
JNJ-3026582
References
1) Wadsworth, S.A., et al. RWJ 67657, a potent, orally active inhibitor of p38 mitogen-activated protein kinase. Journal of Pharmacology and Experimental Therapeutics 291(2), 680-687 (1999).
2) Schafer, P.H., et al. p38 α mitogen-activated protein kinase is activated by CD28-mediated signaling and is required for IL-4 production by human CD4+ CD45RO+ T cells and Th2 effector cells. Journal of Immunology 162(12), 7110-7119 (2016).
