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Arimoclomol
AOB5425
CAS: 289893-25-0
Chemical Name: BRX220; (3Z)-N-[(2R)-2-Hydroxy-3-piperidin-1-ylpropoxy]-1-oxidopyridin-1-ium-3-carboximidoyl chloride
1938 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $17.85 | Total: $89.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 100 | $9.45 | Total: $945.00 |
Overview
Novel stimulator of a normal cellular protein repair pathway, activating the heat shock response and acting at Hsp70, for treatment of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease
Chemical Properties
| Molecular Formula | C14H20ClN3O3 |
| Molecular Weight | 313.78 |
| CAS Numbers | 289893-25-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (3Z)-N-[(2R)-2-Hydroxy-3-piperidin-1-ylpropoxy]-1-oxidopyridin-1-ium-3-carboximidoyl chloride |
| InChl Key | SGEIEGAXKLMUIZ-CYBMUJFWSA-N |
| InChl Code | InChI=1S/C14H20ClN3O3/c15-14(12-5-4-8-18(20)9-12)16-21-11-13(19)10-17-6-2-1-3-7-17/h4-5,8-9,13,19H,1-3,6-7,10-11H2/t13-/m1/s1 |
| SMILES Code | C1CCN(CC1)CC(CON=C(C2=C[N+](=CC=C2)[O-])Cl)O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
BRX220
References
1) Rakonczay Z Jr, et al. Nontoxic heat shock protein coinducer BRX-220 protects against acute pancreatitis in rats. Free Radic Biol Med. 2002 Jun 15;32(12):1283-92.
2) Phukan J. Arimoclomol, a coinducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis. IDrugs. 2010 Jul;13(7):482-96.
