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Cabozantinib (XL184, BMS-907351)
AOB87755
CAS No: 849217-68-1
Chemical Name: N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
For Bulk quantities check : AOB87755B
499 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $15.30 | Total: $76.50 |
| 1 | 10 | $12.96 | Total: $129.60 |
| 1 | 25 | $10.98 | Total: $274.50 |
| 1 | 50 | $9.36 | Total: $468.00 |
| 1 | 100 | $8.10 | Total: $810.00 |
Overview
A pan tyrosine kinase inhibitor that primarily targets VEGFR2 (IC50 = 0.035 nM) and c-Met (IC50 = 1.3 nM) but also inhibits RET, c-Kit, Axl, FLT3, and Tie2 (IC50s = 5.2, 4.6, 7, 11.3, and 14.3 nM, respectively).
Chemical Properties
| Molecular Formula | C28H24FN3O5 |
| Molecular Weight | 501.5 |
| CAS Numbers | 849217-68-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
Storage and Handling
0°C (short term), -20°C (long term), desiccated