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HA-15
AOB8424
CAS No: 1609402-14-3
Chemical Name: N-(4-(3-((5-(Dimethylamino)naphthalene)-1-sulfonamido)phenyl)thiazol-2-yl)acetamide
494 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $12.75 | Total: $63.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 100 | $6.75 | Total: $675.00 |
Overview
Novel antitumor agent, triggering ER stress, exerting anti-melanoma effects and overcoming BRAF inhibitor resistance
Chemical Properties
| Molecular Formula | C23H22N4O3S2 |
| Molecular Weight | 466.58 |
| CAS Numbers | 1609402-14-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | N-(4-(3-((5-(dimethylamino)naphthalene)-1-sulfonamido)phenyl)thiazol-2-yl)acetamide |
| InChl Key | LBSMEKVVMYSTIH-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C23H22N4O3S2/c1-15(28)24-23-25-20(14-31-23)16-7-4-8-17(13-16)26-32(29,30)22-12-6-9-18-19(22)10-5-11-21(18)27(2)3/h4-14,26H,1-3H3,(H,24,25,28) |
| SMILES Code | CC(NC1=NC(C2=CC=CC(NS(=O)(C3=C4C=CC=C(N(C)C)C4=CC=C3)=O)=C2)=CS1)=O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
HA15; HA-15; HA 15
References
1) Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance by Cerezo, Michael; Lehraiki, Abdelali; Millet, Antoine; Rouaud, Florian; Plaisant, Magali; Jaune, Emilie; Botton, Thomas; Ronco, Cyril; Abbe, Patricia; Amdouni, Hella; et al. From Cancer Cell (2016), 29(6), 805-819.
2) Preparation of arylsulfonamido thiazole derivs. as antitumor agents by Rocchi, Stephane; Ballotti, Robert; Benhida, Rachid; Cerezo, Michael; Duca, Maria; Joly, Jean-Patrick From PCT Int. Appl. (2014), WO 2014072486 A1 20140515.
