DDD86481 bis-TFA salt

Name: DDD86481 bis-TFA salt
Brand: AOBIOUS
SKU: AOB12300
Price: 77.35 USD
Availability: InStock

Cat No: AOB12300

Condition

CAS: N/A

Chemical Name: 2,6-Dichloro-N-(3-isobutyl-1,5-dimethyl-1H-pyrazol-4-yl)-4-(2-(piperazin-1-yl)pyridin-4-yl)benzenesulfonamide bis-TFA salt

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Quantity Discount Table - Order More To Get More Price Discount

Quantity	mg	Unit Price ($/mg or $/Unit)	Final Price
1	5	$50.57	Total: $252.87
1	10	$42.84	Total: $428.40
1	25	$36.30	Total: $907.38
1	50	$30.94	Total: $1,547.00
1	100	$26.78	Total: $2,677.50

Overview

Novel potent AfNMT inhibitor, potently inhibiting the NMT mutant and being fungicidal under repressed nmt expression

Chemical Properties

Molecular Formula	C28H32Cl2F6N6O6S
Molecular Weight	765.55
Solubility	DMSO and Alcohol
Purity	98% by HPLC
IUPAC/Chemical Name	2,6-Dichloro-N-(3-isobutyl-1,5-dimethyl-1H-pyrazol-4-yl)-4-(2-(piperazin-1-yl)pyridin-4-yl)benzenesulfonamide bis-TFA salt
SMILES Code

Storage and Handling

0°C (short term), -20°C (long term), desiccated

Synonyms

DDD86481; DDD 86481; DDD-86481

References

1) Liu N, Tu J, Dong G, Wang Y, Sheng C. Emerging New Targets for the Treatment of Resistant Fungal Infections. J Med Chem. 2018 Jan 16. doi: 10.1021/acs.jmedchem.7b01413. [Epub ahead of print] PubMed PMID: 29294275.

2) Fang, W.; Robinson, D. A.; Raimi, O. G.; Blair, D. E.; Harrison, J. R.; Lockhart, D. E.; Torrie, L. S.; Ruda, G. F.; Wyatt, P. G.; Gilbert, I. H.; van Aalten, D. M. N-myristoyltransferase is a cell wall target in aspergillus fumigatus. ACS Chem. Biol. 2015, 10, 1425−1434.