Enzyme Inhibitors

MIF098 View larger

MIF098

AOB33430

CAS 1208448-95-6

Chemical Name: 3-(3-Hydroxybenzyl)-5-methylbenzo[d]oxazol-2(3H)-one

AOBIOUS launched this product in 2022

CITATIONS - Publications That Use AOBIOUS Product

1) Am J Cancer Res 2024;14(2):832-853

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$21.00

$21.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $9.45 Total: $945.00
150 $10.92 Total: $546.00
125 $12.81 Total: $320.25
110 $15.12 Total: $151.20
15 $17.85 Total: $89.25

Data sheet

Molecular FormulaC15H13NO3
Molecular Weight225.27
CAS Numbers1208448-95-6
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymMIF 098; MIF-098
IUPAC/Chemical Name3-(3-Hydroxybenzyl)-5-methylbenzo[d]oxazol-2(3H)-one
References1) HuijingHuang et al., The small molecule macrophage migration inhibitory factor antagonist MIF098, inhibits pulmonary hypertension associated with murine SLE, International Immunopharmacology Volume 76, November 2019, 105874

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Novel antagonist of macrophage migration inhibitory factor (MIF), decreasing RVSP and inhibiting distal pulmonary artery hyperproliferation, muscularization, and collagen deposition in hypoxia challenged mice, inhibiting PASMC proliferation and migration by regulating mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 (MAPK/ERK1/2) signal- and cell-cycle-related proteins, reducing collagen synthesis by inhibiting the TGFβ1/Smad2/Smad3 pathway in cell-based experiments

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