ARI-3099 hydrochloride

ARI-3099 hydrochloride

AOB4262

CAS: 1432499-49-4 (non-HCl salt)
 

Chemical Name: N-(Pyridine-4-carbonyl)-D-Ala-boroPro HCl; N-(Pyridine-4-carbonyl)-(R)-alaninyl-(R)-boroproline hydrochloride

More details

998 Items

$49.50

$49.50 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $42.08 Total: $210.38
110 $35.64 Total: $356.40
125 $30.20 Total: $754.88
150 $25.74 Total: $1,287.00
1100 $22.28 Total: $2,227.50

Overview

Selective and Potent Inhibitor of Fibroblast Activation Protein and Prolyl Oligopeptidase









Chemical Properties

Molecular FormulaC13H17BClN3O4
Molecular Weight325.56
CAS Numbers1432499-49-4 (free base)
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical NameB-[(2R)-1-[(2R)-1-Oxo-2-[(4-pyridinylcarbonyl)amino]propyl]-2-pyrrolidinyl]boronic acid hydrochloride
InChl KeyLCAILAILGOZQNE-SBSPUUFOSA-N
InChl CodeInChI=1S/C13H16BN3O4.ClH/c1-9(16-11(18)10-3-6-15-7-4-10)12(19)17-8-2-5-14(17)13(20)21;/h3-4,6-7,9H,2,5,8H2,1H3,(H,16,18)(H,20,21);1H/t9-;/m1./s1
SMILES CodeO=C(O)B1N(C([C@@H](C)NC(C2=CC=NC=C2)=O)=O)CCC1.[H]Cl

Storage and Handling

0°C (short term), -20°C (long term), desiccated

Synonyms

ARI-3099 ; ARI3099; ARI 3099

References

1) Coppage AL, Heard KR, DiMare MT, Liu Y, Wu W, Lai JH, Bachovchin WW. Human FGF-21 Is a Substrate of Fibroblast Activation Protein. PLoS One. 2016 Mar 10;11(3):e0151269. doi: 10.1371/journal.pone.0151269. PubMed PMID: 26962859; PubMed Central PMCID: PMC4786124.2) Poplawski SE, Lai JH, Li Y, Jin Z, Liu Y, Wu W, Wu Y, Zhou Y, Sudmeier JL, Sanford DG, Bachovchin WW. Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase. J Med Chem. 2013 May 9;56(9):3467-77. doi: 10.1021/jm400351a. PubMed PMID: 23594271; PubMed Central PMCID: PMC4059180.

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