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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3? (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100180250 nM for Cdk5p35, Cdk1cyclin B, Cdk2cyclin E).
Chemical Properties
| Molecular Formula | C16H11N3O2 |
| Molecular Weight | 277.28 |
| CAS Numbers | 160807-49-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | ON=C1C(Nc2ccccc12)=C1C(=O)Nc2ccccc12 |
Storage and Handling
0C Short Term, -20C Long Term
References
Leclerc S, et al. Indirubins inhibit glycogen synthase kinase-3 beta and CDK5p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors? J Biol Chem. 2001 Jan 5;276[1] 251-60.
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