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CYD-2-11 TFA salt
AOB33070
CAS: 1425944-22-4 (free base)
Chemical Name: 2-(2-((2-nitro-9H-fluoren-9-ylidene)methyl)phenoxy)ethan-1-amine
984 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $31.45 | Total: $157.25 |
| 1 | 10 | $26.64 | Total: $266.40 |
| 1 | 25 | $22.57 | Total: $564.25 |
| 1 | 50 | $19.24 | Total: $962.00 |
| 1 | 100 | $16.65 | Total: $1,665.00 |
Overview
Novel potent and selective Bax agonist, targeting the structural pocket proximal to S184 in the C-terminal region of Bax
Chemical Properties
| Molecular Formula | C24H19F3N2O5 |
| Molecular Weight | 472.42 |
| CAS Numbers | 1425944-22-4 (free base) |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (E)-2-(2-((2-nitro-9H-fluoren-9-ylidene)methyl)phenoxy)ethan-1-amine |
| InChl Key | BJIFXXDQMBHYKG-DEDYPNTBSA-N |
| InChl Code | InChI=1S/C22H18N2O3/c23-11-12-27-22-8-4-1-5-15(22)13-20-18-7-3-2-6-17(18)19-10-9-16(24(25)26)14-21(19)20/h1-10,13-14H,11-12,23H2/b20-13+ |
| SMILES Code | NCCOC1=CC=CC=C1/C=C2C3=C(C4=C/2C=CC=C4)C=CC([N+]([O-])=O)=C3 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
CYD-2-11; CYD 2 11; CYD211
References
Li R, Ding C, Zhang J, Xie M, Park D, Ding Y, Chen G, Zhang G, Gilbert-Ross M, Zhou W, Marcus AI, Sun SY, Chen ZG, Sica GL, Ramalingam SS, Magis AT, Fu H, Khuri FR, Curran WJ, Owonikoko TK, Shin DM, Zhou J, Deng X. Modulation of Bax and mTOR for Cancer Therapeutics. Cancer Res. 2017 Jun 1;77(11):3001-3012.
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