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View larger CU-CPD107
AT35349
CAS 2573912-32-8
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $45.90 | Total: $229.50 |
| 1 | 10 | $38.88 | Total: $388.80 |
| 1 | 25 | $32.94 | Total: $823.50 |
| 1 | 50 | $28.08 | Total: $1,404.00 |
| 1 | 100 | $24.30 | Total: $2,430.00 |
Data sheet
| Molecular Formula | C16H21IN2O2 |
| Molecular Weight | 400.25 |
| CAS Numbers | 2573912-32-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(C(C)(C)O)N1C(=C(I)N=C1COCC)C2=CC=CC=C2 |
| References | Yang Y, et al. Tetrasubstituted imidazoles as incognito Toll-like receptor 8?a[nta]gonists. Nat Commun. 2021 Jul 16;12[1] 4351. |
More info
CU-CPD107 is a selective agonist of toll-like receptor 8 (TLR8) and also shows activation activity against ssRNA ligands. CU-CPD107 acts as an inhibitor of TLR8 signaling in the presence of R848 (IC50=13.7 ?M). CU-CPD107 exhibited coagonist activity in the presence of ssRNA, while CU-CPD107 alone could not affect TLR8 signal transduction.